FIGURE

Fig. S6

ID

ZDB-FIG-150513-30

Publication

Ma et al., 2015 - Jag1b is essential for patterning inner ear sensory cristae by regulating anterior morphogenetic tissue separation and preventing posterior cell death

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Fig. S6

fgf8a is expressed in the anterior pro-sensory domain. (A) Whole-mount in situ hybridization, Probe: fgf8 anti-sense. fgf8 is expressed in the anterior prosensory domain at 36 hpf stage. jag1b^+/+, jag1b^+/-, and jag1b^-/- embryos show similar fgf8a expression pattern. (B,C) Whole-mount in situ hybridization of pea3 (B) and erm (C) in WT embryos at 39 hpf stage. Probe: pea3 and erm anti-sense. pea3 and erm expression (arrowheads) is up-regulated in the middle region of the anterior prosensory domain. (D) TUNEL assay of DMSO and SU5402 treated embryos. (E) p-Erk3 immunostaining of DMSO and SU5402 treated embryos. Dorsolateral views with anterior to the left and dorsal up.

Expression Data

Genes:	etv4 etv5b fgf8a
Fish:	WT jag1b^gd2Gt/gd2Gt jag1b^gd2Gt/+
Anatomical Term:	otic vesicle anterior crista
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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