FIGURE
Fig. S8
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- ZDB-FIG-150318-21
- Publication
- Gerlach et al., 2014 - Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta
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Fig. S8
Expression analysis of podocyte specific transcripts nephrin and podocin show a range of failed migration and/or morphogenesis phenotypes in double prkCI/ζ morphant embryos. At 72 hpf, podocytes in wild-type controls (left panels) have migrated and fused at the midline to form a central glomerulus, that express (A) podocin and (B) nephrin (top row 4× magnification; bottom row 10× magnification). In double prkCI/ζ morphants, podocytes do not migrate normally to the midline, as shown by the pattern of (A) podocin and (B) nephrin expressing cells, and furthermore display variable migration patterns. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 396(2), Gerlach, G.F., Wingert, R.A., Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta, 183-200, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.