FIGURE

Fig. 7

ID

ZDB-FIG-140602-18

Publication

Zannino et al., 2014 - prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements

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Fig. 7

Loss of prdm12b has a transient effect on the number of OPC cells. (A–R, V–Y) Expression of olig2 (A–F), sox10 (G–L), dm20 (M–R), MBP (V, W) or fluoromyelin (X, Y) in wild type (A, B, G, H, M–O, V, X), control MO-injected (C, I), PTB MO-injected (D, E, J, K, P–R, W, Y) and PSB MO-injected (F, L) embryos. All embryos are in dorsal view with anterior to the left. Scale bars are 100 μm (A–R) or 35 μm (V–Y). Arrowheads indicate unaffected regions of sox10 expression, while arrows indicate affected regions. Red circles demark the otic vesicles. (S–U) Quantification of reduction in olig2 (S), sox10 (T) and dm20 (U) expression.

Expression Data

Genes:	olig2 plp1a sox10 vsx2
Antibody:	Ab1-mbp
Fish:	WT WT + MO1-prdm12b
Knockdown Reagent:	MO1-prdm12b
Anatomical Terms:	hindbrain glioblast (sensu Vertebrata) hindbrain oligodendrocyte
Stage Range:	Prim-25 to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-prdm12b
Knockdown Reagent:	MO1-prdm12b
Observed In:	central nervous system myelination hindbrain oligodendrocyte
Stage Range:	Prim-25 to Day 6

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 390, Zannino, D.A., Downes, G.B., Sagerström, C.G., prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements, 247-60, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.