Fig. 4
- ID
- ZDB-FIG-140313-38
- Publication
- Fekany et al., 1999 - The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures
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TGF-β signaling suppresses the boz phenotype. (A,B) ntl expression (blue) normally marks notochord precursors (nt) and tail bud in wild-type embryos (A). In boz embryos, ntl expression in notochord precursors is absent (B) (5-7 somites). (C,D hgg1 expression (red) in the prospective hatching gland (hg) of a wild-type embryo (C) is reduced in bozm168 mutants (D). (EG) Overexpression of TARAM-A-D (E), murine Nodal (F) and BMP-Vg1 (G) resulted in ectopic ntl and hgg1 expression domains in the majority of embryos from wild-type and bozm168/m168 parents. (A,B) Dorsal view, (C,D) Frontal view; in all images anterior is to the top. Scale bar, 200 μm. |
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Stage: | 5-9 somites |