FIGURE

Fig. 2

ID

ZDB-FIG-130910-8

Publication

Huang et al., 2013 - Treatment of Glucocorticoids Inhibited Early Immune Responses and Impaired Cardiac Repair in Adult Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Treatment with beclomethasone caused impaired cardiac repair in zebrafish.

Objects were sacrificed at 30 days post ventricular resection; heart sections were stained with aniline blue to distinguish scar tissue from normal tissue. Blue: scar tissue; Orange: normal tissue. (A, A′) In the vehicle control group, the zebrafish regenerated the injured hearts perfectly 1 month after injury. Only a few scar tissue (arrow) was detected in the wound (n = 17). (B, B′) Exposure to beclomethasone (0.25 μM) hindered the cardiac repair process. A large amount of scar tissue (arrow) was found in the wound instead of renewed cardiomyocytes. Meanwhile, obvious blood clots remained, which could be detected (arrow head) (n = 14, scale bar = 100 μm). The dashed lines indicate the approximate amputation plane.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One