FIGURE

Fig. S3

ID

ZDB-FIG-130502-29

Publication

Wada et al., 2013 - Innervation is required for sense organ development in the lateral line system of adult zebrafish

Other Figures

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Fig. S3

(A and B) Single-neuron labeling through plasmid injection in a cldnb-gfp embryo. (A and A′) At 5 days post fertilization (dpf), the neuron innervates a single neuromast. (B and B′) Same fish 1 mo later. The founder neuromast is flanked by a fully differentiated bud neuromast, and both neuromasts are generating a new bud on either side. In both cases, neurites (arrows) invade the bud structures (arrowheads) well before the bud neuromasts begin to differentiate. (C and D) Expression of lgr6 in neuromast cells at 3 dpf (C) and at 11 dpf (D). [Scale bars: 20 μm (C) and 10 μm (D).] (E and F) Rspo2 enhancer trap activity in the neurites that innervate ter1 and ter2 at 7 dpf (E) and in a branch innervating bud neuromast ter2′ at 11 dpf (F). (F) Composite of two frames from a confocal stack, 5.2 μm apart. Maximum projection cannot be used because of high reporter activity in the surrounding mesenchyme.

Expression Data

Gene:	lgr6
Fish:	WT
Anatomical Term:	neuromast
Stage Range:	Protruding-mouth to Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA