FIGURE

Fig. 5

ID

ZDB-FIG-120316-71

Publication

Brusegan et al., 2012 - ccdc80-l1 Is Involved in Axon Pathfinding of Zebrafish Motoneurons

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Fig. 5

ccdc80-l1 is positively regulated by shh.

(A–C) ccdc80-l1 expression in somites and myoseptum resulted strongly inhibited in embryos treated with 5 μM cyclopamine (asterisks in B), in comparison to control embryos at the same developmental stage (A). By converse, over-expression of shh led to an up-regulation of ccdc80-l1 in muscular territories (C). Expression in cranial ganglia (cg) was never perturbed. (D–F) ccdc80-l1 resulted slightly down-regulated in the muscles of heterozygous syu^+/- mutants (E) in comparison to wild type siblings (D). A strikingly down-regulation was observed in homozygous syu^-/- mutants (F). (A–C) Dorsal flat-mount preparations, anterior is up. (D–F) Lateral views of the tails, anterior is left.

Expression Data

Gene:	ccdc80l1
Fish:	WT
Condition:	chemical treatment: Cyclopamine
Anatomical Terms:	cranial ganglion myoseptum somite
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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