FIGURE

Fig. S7

ID

ZDB-FIG-120316-36

Publication

Liao et al., 2012 - Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins

Other Figures

All Figure Page

Back to All Figure Page

Fig. S7

Localization of Appa-red fluorescent protein (RFP) and Aplp2-RFP in the vasculature does not require blood flow. A,B: Lateral views of appa+/is22Gt; Tg(flk1:moesin1-egfp)+/is1; sih+/mn0031Gt (upper) and appa+/is22Gt Tg(flk1:moesin1-egfp)+/is1; sihmn0031Gt/mn0031Gt (bottom) embryos at 2 dpf. C,D: Lateral views of aplp2+/is23Gt; Tg(flk1:moesin1-egfp)+/is1; sih+/mn0031Gt (upper) and aplp2+/is23Gt; Tg(flk1:moesin1-egfp)+/is1; sihmn0031Gt/mn0031Gt (bottom) embryos at 2 dpf. Both Appa-RFP and Aplp2-RFP were detected in the vein region in sih homozygous mutant embryos.

Expression Data

Gene:	mRFP1
Fish:	aplp2^is23Gt/+; tnnt2a^mn0031Gt/+; is1Tg/+ aplp2^is23Gt/+; tnnt2a^{mn0031Gt/mn0031Gt}; is1Tg/+ appa^is22Gt/+; tnnt2a^mn0031Gt/+; is1Tg/+ appa^is22Gt/+; tnnt2a^{mn0031Gt/mn0031Gt}; is1Tg/+
Anatomical Term:	vein
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	aplp2^is23Gt/+; tnnt2a^mn0031Gt/+; is1Tg/+ aplp2^is23Gt/+; tnnt2a^{mn0031Gt/mn0031Gt}; is1Tg/+ appa^is22Gt/+; tnnt2a^mn0031Gt/+; is1Tg/+ appa^is22Gt/+; tnnt2a^{mn0031Gt/mn0031Gt}; is1Tg/+
Observed In:	blood blood circulation blood vasculature heart heart contraction
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.