FIGURE

Fig. S11

ID

ZDB-FIG-111223-6

Publication

Maragh et al., 2011 - Identification of RNA binding motif proteins essential for cardiovascular development

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Fig. S11

rbm24a and rbm24b splice blocked morphants display cardiac defects. Injection of 7.5 ng of rbm24a splice blocking morpholino results in a substantial reduction of full-length transcript (A). Injection of 9 ng of rbm24b splice blocking morpholino results in aberrant splicing of the transcript. There is a reduction of full-length transcript 250 bp fragment and appearance of trace amounts of the shortened frameshift fragment 164 bp and shortened in-frame transcript 109 bp (B). RT-PCR measurement of transcript levels show both rbm24a (42.80% +/- 3.35, P < 6.5 × 10^-4) and rbm24b (40.27 +/- 3.19, P < 4.4 × 10^-5) morphants have significant reduction of transcript levels compared to uninjected controls (C) Error bars are standard deviation, *** P < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.