FIGURE

Fig. 5

ID

ZDB-FIG-110608-17

Publication

Quillien et al., 2011 - BMP signaling orchestrates photoreceptor specification in the zebrafish pineal gland in collaboration with Notch

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Fig. 5

BMP regulates the competence to respond to Notch. (A-C) Confocal projections of control (A), Tg(hs:Gal4);Tg(UAS:Notch^intra) transgenic (B) and Tg(hs:Gal4);Tg(UAS:Notch^intra) transgenic bmp2a-morphant (C) embryos at 48 hours. Heat shock was performed at 14 hours. The effects of the various treatments were monitored by GFP immunostaining in the Tg(HuC:GFP) background. (D,E) Average numbers of Tg(HuC:GFP)+ cells in 48 hour control, Tg(hs:Gal4);Tg(UAS:Notch^intra) transgenic, Tg(hs:Gal4);Tg(UAS:Notch^intra) transgenic bmp2a-morphant and bmp2a-morphant (D) embryos or smad5-morphant embryos (E). Heat shocks were performed at 14 hours. The number (n) of embryos analyzed is noted for each case in D and E. Error bars represent s.d. *P<0.05, ***P<0.0005 using a t-test. Anterior is upwards. Scale bar: 16 μm.

Expression Data

Gene:	EGFP
Fish:	kca3Tg; kca4Tg; knu3Tg
Condition:	heat shock
Anatomical Term:	neuron
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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