FIGURE

Fig. S4

ID

ZDB-FIG-100809-33

Publication

Xie et al., 2010 - A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development

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Fig. S4

Bradykinin induces BRB breakdown. At 5 dpf, 20 double transgenic (l-fabp:DBP-EGFP;flk1:mCherry) larvae were injected with 2 μL of 20 μM bradykinin in the right eye (B, B′, C and C′). 3 hours after injection, the BRB was found to be disrupted in 18 injected eyes, as indicated by the leakage of DBP-EGFP (green) (B, C) from the hyaloid vessels (red) (B′C′) which showed normal morphology. No leakage was observed in any of the BSA injected contra-lateral negative control eyes (A, A′).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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