FIGURE

Fig. 2

ID

ZDB-FIG-100223-24

Publication

Camarata et al., 2010 - Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation

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Fig. 2

Knock-down of pdlim7 perturbs heart and pectoral fin development. (A–C) Lateral view of wild-type (A), MO2, (B) and rescued MO2 (C) injected embryos at 48 hpf. (D–F) Magnification of hearts of wild-type (D), MO1 (E), and MO2 (F) injected embryo at 48 hpf. Arrowhead in E and F indicates string-like heart. Embryo in F treated with 0.0045% PTU to inhibit pigmentation over the heart. (G–I) Magnification of pectoral fins of wild-type (G), MO1 (H), and MO2 (I) morphants at 48 hpf (arrows). The head is to the left.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-pdlim7 WT + MO4-pdlim7
Knockdown Reagents:	MO3-pdlim7 MO4-pdlim7
Observed In:	developmental growth involved in morphogenesis heart contraction heart looping pectoral fin pectoral fin morphogenesis pericardium post-vent region skeletal muscle tissue development thigmotaxis trunk musculature (all 10)
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 337(2), Camarata, T., Krcmery, J., Snyder, D., Park, S., Topczewski, J., and Simon, H.G., Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation, 233-245, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.