FIGURE

Fig. S1

ID

ZDB-FIG-091201-1

Publication

Siekmann et al., 2009 - Chemokine signaling guides regional patterning of the first embryonic artery

Other Figures

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Fig. S1

Absence of the notochord specifically affects posterior dorsal aorta development. Wildtype (A, B) or no tail ^b160 mutant embryos (C, D) at the 22 somite stage (ss) in situ hybridized with a probe for kdrl marking all endothelial cells. Anterior is to the left, dorsal up. A, Anterior region of a wildtype embryo showing the forming paired anterior lateral dorsal aortae (arrows), or the posterior lateral dorsal aortae (arrowheads). A, Posterior region of the same embryo as in A, showing the single posterior dorsal aorta (double arrow, DA). C, In no tail ^b160 mutant embryos, formation of the anterior lateral dorsal aortae occurs normally (arrows), while the posterior dorsal aortae (arrowheads indicate individual endothelial cells close to the midline) do not form properly. D, Posterior region of the same embryo as in C, showing failure of angioblasts to migrate towards the midline (double arrow, compare to double arrow in B).

Expression Data

Gene:	kdrl
Fish:	WT tbxta^b160/b160
Anatomical Term:	blood vasculature blood vessel endothelial cell
Stage:	20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	tbxta^b160/b160
Observed In:	dorsal aorta lateral dorsal aorta vasculogenesis
Stage:	20-25 somites

Phenotype Detail

Acknowledgments

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