FIGURE

Fig. S4

ID

ZDB-FIG-090904-50

Publication

Jing et al., 2009 - Zebrafish ale oko, an essential determinant of sensory neuron survival and the polarity of retinal radial glia, encodes the p50 subunit of dynactin

Other Figures

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Fig. S4

ale oko function in mitotic spindle orientation. (A) Schematic representation of mitotic spindle orientation relative to the apical surface of the retinal neuroepithelium. The angle between the spindle axis (red line) and the apical surface of the retinal neuroepithelium (blue line) was measured. (B,B′) Transverse sections through wild-type (B) and ako mutant (B′) neuroepithelia were stained with an anti-α-tubulin antibody to visualize mitotic spindles (green). Apical is up. (C,D) Quantification of spindle orientation in wild-type (C) and ako mutant (D) retinae. The alignment of the mitotic spindle is clearly less consistent in ako^jj50 retinae. Scale bar: 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dctn2^jj50/jj50 (AB)
Observed In:	establishment of mitotic spindle orientation
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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