FIGURE

Fig. 6

ID

ZDB-FIG-090804-48

Publication

Drerup et al., 2009 - Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Disc1 repressed foxd3 and sox10 expression. (A) Injection of 200 pg of gfp mRNA into one cell of a two- to four-cell-stage embryo resulted in unilateral expression at 5s. Dotted line outlines the edge of the embryo. (B-E) Asymmetrical overexpression of the human ortholog of disc1 resulted in a unilateral loss of foxd3 (B,C) and sox10 (D,E) expression (arrows). Expression of myod1 was normal. Dorsal views with anterior to the left. (F-I) Overexpression of Foxd3 resulted in an expansion of sox10 expression (arrows in H,I) similar to that seen in Disc1 morphants. F and G are lateral views, H and I, dorsal views, both with anterior to the left.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development