FIGURE

Fig. S3

ID

ZDB-FIG-090113-38

Publication

Lin et al., 2009 - Distinct functions of Wnt/{beta}-catenin signaling in KV development and cardiac asymmetry

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Fig. S3

The effect of Wnt/β-catenin signaling on midline development. (A-P) Midline structures were not affected by alterations of Wnt signaling, as revealed by staining for the midline mesendodermal markers axial (A-H) or gsc and ntl (I-P). Embryos were co-stained with pax2 as an anteroposterior reference. Shown are dorsal views with anterior to the top of tailbud-staged embryos. (Q-T) lefty1 expression in the notochord was abolished in wnt3 morphants (T), but not in apc morphants (R) or in embryos injected with wnt3 RNA (S). Shown are dorsal views of 21-somite staged embryos with anterior to the top.

Expression Data

Genes:	foxa2 gsc lft1 pax2a tbxta
Fish:	TL TL + MO1-apc TL + MO1-wnt3a
Knockdown Reagents:	MO1-apc MO1-wnt3a
Anatomical Terms:	midbrain hindbrain boundary neural keel notochord prechordal plate
Stage Range:	Bud to 20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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