FIGURE

Fig. 6

ID

ZDB-FIG-080804-26

Publication

Schauerte et al., 1998 - Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish

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Fig. 6

Zn5 antibody staining of secondary motorneurons in a wildtype (A) and a syu^tbx392/syu^t4 mutant (B) embryo at 52 hpf. In syu mutant embryos the axons of the secondary motorneurons (indicated by arrows) fail to branch and instead cease to extend or grow further ventrally in an abnormal pattern. Zn5 staining of retinal axon projections in wild-type (C) and syu mutant alleles (D-F) at 52 hpf. In wild-type embryos, the retinal ganglion cell axons have crossed the midline where the optic chiasm is formed (arrow) and grow towards the tectum on the contralateral side. In syu mutant embryos, these retinal axons frequently fail to cross the midline and remain on the ipsilateral side (arrows) or, if they do cross the midline, frequently grow abnormally and in many cases only form very thin axon bundles (arrowheads).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	Df(Chr07)t4/t4 shha^tbq70/tbq70 shha^tbx392/+; Df(Chr07)t4/+
Observed In:	motor neuron axon guidance retina development in camera-type eye retinal ganglion cell axon guidance
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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