FIGURE

Fig. 1

ID

ZDB-FIG-080528-14

Publication

Langenau et al., 2005 - Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia

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Fig. 1

Stable transgenic rag2-EGFP-mMyc zebrafish develop GFP-labeled thymic lymphoma, which progresses to T-ALL. Fluorescence microscopic analysis at 50 days of life showing the thymus of control rag2-GFP transgenic fish (A) and massive GFP-labeled cellular dissemination of leukemic lymphoblasts in rag2-EGFP-mMyc transgenic fish (B). Fish are oriented with anterior to the left and dorsal to the top. Arrowheads mark location of the thymus (T).

Expression Data

Gene:	GFP
Fish:	zdf8Tg
Anatomical Term:	thymus
Stage:	Days 45-89

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zdf6Tg
Observed In:	pro-T cell precursor T-cell lymphoblastic lymphoma/leukaemia thymus
Stage:	Days 45-89

Phenotype Detail

Acknowledgments

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