FIGURE

Fig. S1

ID

ZDB-FIG-080410-21

Publication

Kiener et al., 2008 - Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos

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Fig. S1

The asymmetric distribution of plasma membrane proteins is maintained in tjp3/zo-3 morphants. Epithelial cell polarization in the pronephric ducts. Immunofluorescence on cryosections: anti-Tjp3/Zo-3 (green) and anti-E-cadherin (red) (a-f); anti- PKCζ (green) and anti-Na+/K+-ATPase (red) (g-l). Control morpholino at 1 dpf (a, g) and 2 dpf (d, j); tjp3/zo-3 splice morpholino at 1 dpf (b, h) and 2 dpf (e, k) and tjp3/zo-3 translation blocking morpholino at 1 dpf (c, I) and 2 dpf (f, l). Note the strong reduction of Tjp3/Zo-3 protein from the apical side of the pronephric ducts in morphants (arrows), whereas E-cadherin or Na+/K+- ATPase staining on the basolateral membrane or PKCζ labeling on the apical membrane is not affected.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 316(1), Kiener, T.K., Selptsova-Friedrich, I., and Hunziker, W., Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos, 36-49, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.