FIGURE

Fig. 5

ID

ZDB-FIG-080331-21

Publication

Hanington et al., 2008 - Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio)

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Fig. 5

Embryonic and larval expression patterns of lifr. (A, B) At 24 hpf, lifr was highly expressed in the forebrain, midbrain and notochord. (C) lifr was also visible in the otic vesicle (OV) at 24 hpf. (D) At 48 hpf, lifr was localized in regions of the cranial sensory ganglia (asterisk, *), retina and forebrain. (E) Expression pattern of lifr at 72 hpf was similar to that at 48 hpf. lifr was expressed in regions of the cranial sensory ganglia (*) and forebrain. (F) lifr was not expressed in trunk muscle and trunk neurons. (f), forebrain; (m), midbrain; (h), hindbrain; (cb), cerebellum; (rpe), retinal pigmented epithelium.

Expression Data

Gene:	lifrb
Fish:	AB
Anatomical Terms:	cranial ganglion forebrain midbrain notochord otic vesicle retina retinal pigmented epithelium
Stage Range:	Prim-5 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-lifrb rw0Tg + MO1-lifrb
Knockdown Reagent:	MO1-lifrb
Observed In:	anterior commissure axon cranial nerve V cranial nerve VII cranial nerve X hindbrain hindbrain axon nervous system development neural tube Rohon-Beard neuron optic tectum axon spinal cord motor neuron trigeminal ganglion axon
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 314(2), Hanington, P.C., Patten, S.A., Reaume, L.M., Waskiewicz, A.J., Belosevic, M., and Ali, D.W., Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio), 250-260, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.