FIGURE

Fig. S1

ID

ZDB-FIG-070801-17

Publication

Jin et al., 2007 - A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos

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Fig. S1

The number of endothelial cells is reduced in min^s202 and grc^s635. (A–D) Transverse sections of 30 hpf Tg(flk1:EGFP)^s843 wild-type (A) and min^s202 mutant (B) embryos, and 36 hpf wild-type (C) and grc^s635 mutant (D) embryos, visualized for Tg(flk1:EGFP)^s843 expression (green), β-Catenin (red), and TOPRO (blue). White arrows point to the apparent lack of endothelial cells in mutant embryos (as assessed by Tg(flk1:EGFP)^s843 expression). In wild-type embryos, 6 to 7 endothelial cells are present per any given optical section. In comparison, min^s202 mutant embryos have less than one endothelial cell per section (n = 10), and grc^s635 mutant embryos have less than 3 endothelial cells per section (n = 14).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	etsrp^s635/s635; s843Tg med14^s231/s231; s843Tg
Observed In:	blood vessel endothelial cell
Stage Range:	Prim-15 to Prim-25

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 307(1), Jin, S.W., Herzog, W., Santoro, M.M., Mitchell, T.S., Frantsve, J., Jungblut, B., Beis, D., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Field, H.A., Chi, N.C., Wehman, A.M., Baier, H., and Stainier, D.Y., A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos, 29-42, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.