FIGURE

Fig. 6

ID

ZDB-FIG-070613-61

Publication

Catalano et al., 2007 - Zebrafish dou yan mutation causes patterning defects and extensive cell death in the retina

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

The dou yan^mi234 mutation does not disrupt cell proliferation in the retina.A-F: M-phase nuclei, visualized by anti-phospho-Histone 3 antibody (PH3, red), are observed in both wild-type (A-C) and mutant retinas (D-F) at 3 days postfertilization (dpf). All nuclei are stained with YO-PRO-1 iodide (YO, green). C is the merged image of A and B. F is the merged image of D and E. G: The average number of PH3-positive cells per 3,600 μm² in mutant retinas is similar to wild-type retinas at 40 hours postfertilization (hpf), 48 hpf, and 72 hpf. The error bars denote the standard error of the mean. H: Bromodeoxyuridine (BrdU) labeling of the wild-type retina between 49 hpf and 51.5 hpf reveals proliferating cells in most regions of the retina. Arrowheads indicate BrdU-negative basal regions in the wild-type retina. I: BrdU labeling of dou yan mutants between 49 hpf and 51.5 hpf confirms that many retinal cells are actively synthesizing DNA. Scale bars = 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.