FIGURE

Fig. S2

ID

ZDB-FIG-070219-16

Publication

Hernandez et al., 2007 - Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development

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Fig. S2

The ventral hindbrain is sensitive to low concentrations of RA. RNA in situ hybridizations showing vhnf1 (blue), and krox20 and pax2a (both in red) expression at the 3-somite stage (11 hpf). In embryos treated with 10 nM RA, which causes very mild, if any, patterning defects, the ventral-most hindbrain is specifically posteriorized, corresponding with the absence of cyp26c1 expression there (arrow in B). Scale bar: 100 μm.

Expression Data

Genes:	egr2b hnf1ba pax2a
Fish:	cyp26a1^rw716/rw716
Condition:	chemical treatment: all-trans-retinoic acid
Anatomical Terms:	midbrain hindbrain boundary neural keel presumptive rhombomere 3 presumptive rhombomere 5 presumptive rhombomere 6 presumptive rhombomere 7 presumptive rhombomere 8
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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