FIGURE

Fig. 2

ID

ZDB-FIG-060825-2

Publication

Koudijs et al., 2005 - The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway

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Fig. 2

Phenotypes of uki^hu418B Mutant Embryos
(A and B) Lateral view of a wild-type (wt) and uki^hu418B mutant.
(B) Showing an increased volume of the head. The size of the pupil is reduced in the uki^hu18B mutant without affecting the size of the eye.
(C–E) The size of the pupil is reduced in the uki^hu18B mutant compared to wild-type, without affecting the size of the eye. Measurements revealed that the length and width of the pupil is significantly reduced in the uki^418B mutant (n = 5, *p < 0,001).
(F–H) Pectoral fins showing the increased size of an uki^418B mutant in which the dorsal/ventral (D/V) size of the pectoral fin is increased by 50%, (n = 3, *0.01 < p < 0.02).
(I) The anterior/posterior size is not significantly affected, but the fin area has increased by 65%; (n = 3, p < 0.001).
(J and K) uki^hu418B mutants lack the dorsolateral septum in the ear (arrowhead). Scale bar is 100 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hhip^{hu418b/hu418b}
Observed In:	dorsolateral septum eye head pectoral fin pupil
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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