FIGURE

Fig. 7

ID

ZDB-FIG-060825-12

Publication

Koudijs et al., 2005 - The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway

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Fig. 7

Phenotypic Analysis of dre/uki/lep Triple Mutants
(A) Wild-type (wt) embryo at 96 hpf.
(B–E) The indicated double and triple mutants do not show severe enhancement of the phenotype.
(F–I) dre/lep double mutants have an ear phenotype comparable with a single mutant. In the uki/lep and dre/uki/lep triple mutants, the epithelial projections (arrows) fail to grow out to fuse in the middle of the ear to form the ear lumen.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hhip^{tc256d/tc256d}; ptch1^tj222/tj222 hhip^{tc256d/tc256d}; sufu^{tm146d/tm146d} ptch1^tj222/tj222; sufu^{tm146d/tm146d} hhip^{tc256d/tc256d}; ptch1^tj222/tj222; sufu^{tm146d/tm146d}
Observed In:	dorsolateral septum ear morphogenesis head lens pectoral fin semicircular canal
Stage:	Day 4

Phenotype Detail

Acknowledgments

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