FIGURE

Fig. 5

ID

ZDB-FIG-050510-15

Publication

Shimizu et al., 2005 - Interaction of Wnt and caudal-related genes in zebrafish posterior body formation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Cooperation of FGF and Wnt signaling for the cdx1a and cdx4 expression. Expression of cdx1a and cdx4 at the 3-somite stage in wild-type embryos (wt, A, B), SU5402 (an inhibitor of FGF receptors)-treated embryos (C, D), a dominant negative Xenopus FGF receptor 1 (XFD) RNA (500 pg)-injected embryos (E, F), SU5402-treated wnt3a/wnt8 morphant embryos (G, H), and embryos receiving an injection of 6 pg of pCS2 + fgf8 (I, J). The cdx1a and cdx4 expression was slightly reduced in the SU5402-treated embryos, and more strongly reduced in the embryos defective in both Wnt3a/Wnt8 and FGF signaling. In contrast, expression of cdx1a and cdx4 was expanded anteriorly in the fgf8-misexpressing embryos. Lateral views with dorsal to the right.

Expression Data

Genes:	cdx1a cdx4
Fish:	WT WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a
Condition:	chemical treatment: SU5402
Knockdown Reagents:	MO1-wnt3a MO1-wnt8a MO2-wnt8a
Anatomical Terms:	segmental plate somite
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 279(1), Shimizu, T., Bae, Y.K., Muraoka, O., and Hibi, M., Interaction of Wnt and caudal-related genes in zebrafish posterior body formation, 125-141, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.