FIGURE

Fig. S3

ID

ZDB-FIG-050506-12

Publication

Kramer-Zucker et al., 2005 - Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. S3

Rescue of IFT morphant phenotype by hippi mRNA injection. Overexpression of zebrafish hippi by injection of capped RNA (2.3 ng) does not cause a visible phenotype, but is capable of rescuing the phenotype caused by injection of 4.6 nl of 0.1 mmol/l hippi SP morpholino. All 55 morpholino-injected embryos showed pronephric cyst formation (arrow and * in histological cross section) and some degree of hydrocephalus (arrowhead and ** in histological cross section), with 48 of 55 also having a ventrally bent body axis, whereas 6 appeared normal. Of the 44 co-injected embryos, 4 had a bent body axis, and hydrocephalus, but no renal cyst formation. Four had a straight body axis and no hydrocephalus, but kidney cysts, and 36 appeared wild type, which was confirmed by histology.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development