FIGURE

Fig. 5

ID

ZDB-FIG-041208-1

Publication

Lorent et al., 2004 - Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy

Other Figures

Fig. 5

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Fig. 5

Liver expression of zebrafish jagged and notch genes. (A-C) Lateral view of wild-type 72-hpf larvae processed for RNA in situ hybridization using jagged 1 (A), jagged 2 (B) and jagged 3 (C) antisense probes. All three jagged genes are expressed in the larval liver (arrow), but jagged 2 expression is most pronounced. Expression in the branchial arches is also evident. (D-G) Lateral view of wild-type 72-hpf larvae processed for RNA in situ hybridization using notch 1a (D), notch 1b (E), notch 2 (F) and notch 5 (G) probes. All notch genes are expressed in the developing larval liver and the branchial arches.

Expression Data

Genes:	jag1a jag1b jag2b notch1a notch1b notch2 notch3
Fish:	WT
Anatomical Terms:	liver pharyngeal arch 3-7 skeleton
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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