CRISPR

CRISPR10-stat3

ID

ZDB-CRISPR-241015-1

Name

CRISPR10-stat3

Previous Names

None

Target

Sequence

5' - GGTAGACCAGCGGCGACACT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mdu36	stat3

Expression

Gene expression in Wild Types + CRISPR10-stat3

No data available

Phenotype

Phenotype resulting from CRISPR10-stat3

No data available

Phenotype of all Fish created by or utilizing CRISPR10-stat3

Phenotype	Fish	Conditions	Figures
caudal fin fin regeneration disrupted, abnormal	stat3^mdu36/mdu36	amputation: caudal fin	Figure 6 from Sobah et al., 2023
whole organism viability, abnormal	stat3^mdu36/mdu36	standard conditions	Figure 2 from Sobah et al., 2023
vertebral column curved, abnormal	stat3^mdu36/mdu36	standard conditions	Figure 2 , Figure 3 from Sobah et al., 2023
ceratohyal bone decreased size, abnormal	stat3^mdu36/mdu36	standard conditions	Figure 4 from Sobah et al., 2023
mandibular arch skeleton morphology, abnormal	stat3^mdu36/mdu36	standard conditions	Figure 2 from Sobah et al., 2023
whole organism decreased size, abnormal	stat3^mdu36/mdu36	standard conditions	Figure 1 from Sobah et al., 2023
whole organism viability, abnormal	stat3^mdu36/mdu36	amputation: caudal fin	Figure 6 from Sobah et al., 2023
innate immune response decreased magnitude, abnormal	stat3^mdu36/mdu36; gl22Tg	standard conditions	Figure 7 from Sobah et al., 2023
caudal fin macrophage decreased amount, abnormal	stat3^mdu36/mdu36; gl22Tg	standard conditions	Figure 7 from Sobah et al., 2023
innate immune response decreased magnitude, abnormal	stat3^mdu36/mdu36; i114Tg	standard conditions	Figure 7 from Sobah et al., 2023
caudal fin neutrophil decreased amount, abnormal	stat3^mdu36/mdu36; i114Tg	standard conditions	Figure 7 from Sobah et al., 2023

Citations