CRISPR

CRISPR4-lrp5

ID

ZDB-CRISPR-230207-1

Name

CRISPR4-lrp5

Previous Names

None

Target

lrp5 (1)

Sequence

5' - GGGTCGCTCAGAGTCTGCAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
biu102	lrp5

Expression

Gene expression in Wild Types + CRISPR4-lrp5

No data available

Phenotype

Phenotype resulting from CRISPR4-lrp5

No data available

Phenotype of all Fish created by or utilizing CRISPR4-lrp5

Phenotype	Fish	Conditions	Figures
lepidotrichium proximal side bifurcated, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 6 from Khrystoforova et al., 2022
cranial vault bone mineralization decreased process quality, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
cranium mef2d expression increased amount, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 5 from Khrystoforova et al., 2022
cranium mmp9 expression increased amount, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 5 from Khrystoforova et al., 2022
vertebral column curved, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
vertebral column kinked, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
opercle bone mineralization decreased process quality, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
skeletal tissue decreased mass density, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
whole organism viability, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 1 from Khrystoforova et al., 2022
whole organism decreased life span, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 1 from Khrystoforova et al., 2022
cranial vault decreased mass density, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
scale bone mineralization decreased process quality, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 6 from Khrystoforova et al., 2022
cranium map3k5 expression increased amount, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 5 from Khrystoforova et al., 2022
ventral mandibular arch bone mineralization decreased process quality, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022
scale osteoclast active, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 6 from Khrystoforova et al., 2022
caudal fin Ab1-lrp5 labeling absent, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 1 from Khrystoforova et al., 2022
cranium mmp13a expression increased amount, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 5 from Khrystoforova et al., 2022
nasal bone increased angle to mouth, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 3 from Khrystoforova et al., 2022
parasphenoid decreased length, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 3 from Khrystoforova et al., 2022
parasphenoid malformed, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 3 from Khrystoforova et al., 2022
cranium acp5a expression increased amount, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 5 from Khrystoforova et al., 2022
head deformed, abnormal	lrp5^{biu102/biu102} (AB)	standard conditions	Figure 2 from Khrystoforova et al., 2022

Citations