ZFIN All Figures, Robens <i>et al.</i>, 2022

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Antibody:	Ab2-pcdh19
Fish:	WT pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560}
Anatomical Term:	head
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560}
Observed In:	head
Stage:	Adult

Phenotype details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560} WT + CRISPR6-pcdh19 + CRISPR7-pcdh19 pcdh19^zf3559/+ pcdh19^zf3560/+
Knockdown Reagents:	CRISPR6-pcdh19 CRISPR7-pcdh19
Observed In:	optic tectum excitatory postsynaptic potential
Stage:	Day 6

Phenotype details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Antibodies:	Ab9-mapk Ab12-mapk
Fish:	pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560} WT + CRISPR6-pcdh19 + CRISPR7-pcdh19 pcdh19^zf3559/+ pcdh19^zf3560/+
Knockdown Reagents:	CRISPR6-pcdh19 CRISPR7-pcdh19
Anatomical Term:	retinotectal tract
Stage:	Day 5

Expression / Labeling details

PHENOTYPE:

Fish:	pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560} WT + CRISPR6-pcdh19 + CRISPR7-pcdh19
Knockdown Reagents:	CRISPR6-pcdh19 CRISPR7-pcdh19
Observed In:	retinotectal tract
Stage:	Day 5

Phenotype details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	WT pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560} WT + CRISPR6-pcdh19 + CRISPR7-pcdh19 pcdh19^zf3559/+ pcdh19^zf3560/+ mitfa^w2/w2; jf4Tg mitfa^w2/w2; jf4Tg + CRISPR6-pcdh19 + CRISPR7-pcdh19 mitfa^w2/w2; pcdh19^zf3559/+; jf4Tg mitfa^w2/w2; pcdh19^zf3560/+; jf4Tg
Condition:	chemical treatment by environment: pentetrazol
Knockdown Reagents:	CRISPR6-pcdh19 CRISPR7-pcdh19
Observed In:	regulation of neuronal action potential swimming behavior
Stage Range:	Day 6 to Adult

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	DsRed GFP
Fish:	nns14Tg; ot1Tg pcdh19^zf3559/+; nns14Tg; ot1Tg pcdh19^zf3560/+; nns14Tg; ot1Tg
Anatomical Terms:	brain neuron forebrain neuron midbrain neuron optic tectum neuron
Stage:	Day 5

Expression / Labeling details

PHENOTYPE:

Fish:	nns14Tg; ot1Tg nns14Tg; ot1Tg + CRISPR6-pcdh19 + CRISPR7-pcdh19 pcdh19^zf3559/+; nns14Tg; ot1Tg pcdh19^{zf3559/zf3559}; nns14Tg; ot1Tg pcdh19^zf3560/+; nns14Tg; ot1Tg pcdh19^{zf3560/zf3560}; nns14Tg; ot1Tg
Knockdown Reagents:	CRISPR6-pcdh19 CRISPR7-pcdh19
Observed In:	optic tectum inhibitory interneuron
Stage:	Day 5

Phenotype details

text only

Unillustrated author statements

PHENOTYPE:

Fish:	pcdh19^{zf3559/zf3559} pcdh19^{zf3560/zf3560}
Observed In:	whole organism
Stage:	Adult

Phenotype details

Acknowledgments

Full text @ Neurobiol. Dis.

Robens et al., 2022

ZDB-PUB-220424-28
PMID:35460869

Mosaic and non-mosaic protocadherin 19 mutation leads to neuronal hyperexcitability in zebrafish

Robens et al., 2022 ZDB-PUB-220424-28 PMID:35460869

Mosaic and non-mosaic protocadherin 19 mutation leads to neuronal hyperexcitability in zebrafish

Robens et al., 2022

ZDB-PUB-220424-28
PMID:35460869