ZFIN All Figures, Hübner <i>et al.</i>, 2018

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	EGFP
Fish:	s843Tg mu279Tg; s843Tg mu201Tg; s843Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Anatomical Terms:	brain vasculature brain vasculature vascular sprouts
Stage:	Prim-15

Expression / Labeling details

PHENOTYPE:

Fish:	s843Tg mu201Tg; s843Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Observed In:	central artery vascular sprouts
Stage:	Prim-15

Phenotype details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	mu240Tg s896Tg mu201Tg; mu240Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Observed In:	basilar artery brain vasculature angiogenic sprout fusion brain vasculature branching involved in blood vessel morphogenesis central artery central artery blood vessel lumenization
Stage:	Long-pec

Phenotype details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	TagBFP
Antibodies:	Ab1-cdh5 Ab1-tjp1
Fish:	mu293Tg mu240Tg; mu279Tg mu201Tg; mu240Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Anatomical Terms:	brain vasculature blood vessel endothelial cell brain vasculature cell-cell junction
Stage:	High-pec

Expression / Labeling details

PHENOTYPE:

Fish:	mu293Tg mu201Tg; mu240Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Observed In:	brain vasculature cell-cell junction
Stage:	High-pec

Phenotype details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	axin2 cdh5 esama lef1 prickle1a tcf15
Antibody:	Ab1-cdh5
Fish:	s843Tg rk8Tg; ubs3Tg mu201Tg; s843Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Anatomical Term:	brain vasculature blood vessel endothelial cell
Stage Range:	Prim-15 to High-pec

Expression / Labeling details

PHENOTYPE:

Fish:	s843Tg rk8Tg; ubs3Tg mu201Tg; s843Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Observed In:	brain vasculature blood vessel endothelial cell
Stage Range:	Prim-15 to High-pec

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	mu240Tg mu240Tg + CRISPR1-s1pr1 mu201Tg; mu240Tg
Conditions:	chemical treatment by environment: IWR-1-endo chemical treatment by environment: IWR-1-endo chemical treatment by environment: IWR-1-endo heat shock chemical treatment by environment: VPC 23019, heat shock
Knockdown Reagent:	CRISPR1-s1pr1
Observed In:	central artery central artery blood vessel lumenization
Stage:	Long-pec

Phenotype details

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	mu240Tg mu211Tg; s896Tg; ubs3Tg mu212Tg; s896Tg; ubs3Tg
Conditions:	chemical treatment by environment: IWR-1-endo chemical treatment by environment: IWR-1-endo
Observed In:	central artery central artery blood vessel lumenization
Stage:	Long-pec

Phenotype details

Fig. S4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	esama
Fish:	s843Tg mu201Tg; s843Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Anatomical Term:	brain vasculature vascular sprouts
Stage Range:	Prim-15 to High-pec

Expression / Labeling details

PHENOTYPE:

Fish:	s843Tg cdh5^ubs8/ubs8; mu240Tg esama^ubs19/ubs19; ubs16Tg mu201Tg; s843Tg
Conditions:	chemical treatment by environment: IWR-1-endo heat shock
Observed In:	brain vasculature angiogenic sprout fusion brain vasculature vascular sprouts central artery blood vessel lumenization
Stage Range:	Prim-15 to Long-pec

Phenotype details

Fig. S5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	s1pr1 s1pr2 s1pr5a
Fish:	rk8Tg; ubs3Tg
Anatomical Term:	brain vasculature blood vessel endothelial cell
Stage:	Prim-25

Expression / Labeling details

Fig. S8

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	adgra2^s984/s984; mu240Tg
Conditions:	chemical treatment by environment: TY 52156 chemical treatment by environment: VPC 23019
Observed In:	central artery blood vessel lumenization
Stage:	Long-pec

Phenotype details

Acknowledgments

Full text @ Nat. Commun.

Hübner et al., 2018

ZDB-PUB-181219-1
PMID:30451830

Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling

Hübner et al., 2018 ZDB-PUB-181219-1 PMID:30451830

Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling

Hübner et al., 2018

ZDB-PUB-181219-1
PMID:30451830