| ZFIN ID: ZDB-EXP-190924-3 |
Experiment Conditions Description: chemical treatment by environment: IWR-1-endo, chemical treatment by environment: VPC 23019
| chemical treatment by environment: IWR-1-endo |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | IWR-1-endo |
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| Synonyms: | 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, IRW1 |
| Definition: | A dicarboximide having an endo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. |
| Ontology: | ChEBI [CHEBI:62882] ( EBI ) |
| chemical treatment by environment: VPC 23019 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | VPC 23019 |
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| Synonyms: | (2R)-2-amino-3-(3-octylanilino)-3-oxopropyl dihydrogen phosphate, (2R)-2-amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamide, (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester, N-(3-octylphenyl)-O-phosphono-D-serinamide, VPC-23019, VPC23019 |
| Definition: | A secondary carboxamide resulting from the formal condensation of the carboxy group of O-phospho-D-serine with the amino group of m-octylaniline. An analogue of sphingosine-1-phosphate (S1P), it is a potent antagonist for both S1P1 and S1P3 receptors. It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells. |
| Ontology: | ChEBI [CHEBI:144948] ( EBI ) |
| Publication: | Hübner et al., 2018 |
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