FIGURE SUMMARY
Title

Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF

Authors
Xia, M., Chen, K., Yao, X., Xu, Y., Yao, J., Yan, J., Shao, Z., Wang, G.
Source
Full text @ Cell Rep.
Fig. 2

Knocking Down Med23 Inhibits Pigmentation in Zebrafish

(A) Zebrafish embryos injected with Ctrl MO, Med23 MO-1, or Med23 MO-2 were analyzed. The images show dorsal views, with the anterior to the right.

(B) Melanin content of Ctrl MO, Med23 MO-1, and Med23 MO-2 embryos. ∗∗∗p < 0.001; error bars indicate SEM.

(C and D) qRT-PCR analysis of the pigmentation-related genes Trp2 (C) and Mitf (D) in zebrafish at the indicated time points. The expression was normalized to Rbl13a. Error bars indicate SEM.

EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage Range: Shield to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Shield to Protruding-mouth
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Rep.
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