Gene
dct
- ID
- ZDB-GENE-000508-1
- Name
- dopachrome tautomerase
- Symbol
- dct Nomenclature History
- Previous Names
-
- TRP-2
- trp2
- tyrosinase-related protein-2
- zgc:109860
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have dopachrome isomerase activity. Predicted to be involved in developmental pigmentation; generation of neurons; and melanin biosynthetic process from tyrosine. Predicted to localize to melanosome. Is expressed in several structures, including eye; female organism; immature eye; integument; and neural crest. Orthologous to human DCT (dopachrome tautomerase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 102 figures from 74 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pennamen et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Oculocutaneous albinism, type VIII | 619165 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| oculocutaneous albinism | WT + MO1-dct | standard conditions | Pennamen et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Di-copper centre-containing domain superfamily | Tyrosinase and Hemocyanin | Tyrosinase copper-binding domain |
|---|---|---|---|---|
|
UniProtKB:A1L1Y0
|
513 |
Interactions and Pathways
No data available
Plasmids
No data available