| Phenotype: | oligodendrocyte myelination disrupted, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | oligodendrocyte |
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| Synonyms: | oligodendroglia |
| Definition: | A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. |
| Ontology: | Anatomy Ontology [ZFA:0009076] |
| Name: | myelination |
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| Synonyms: | myelinogenesis |
| Definition: | The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. |
| Ontology: | GO: Biological Process [GO:0042552] QuickGO AmiGO |
| Name: | disrupted |
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| Synonyms: | |
| Definition: | A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001507] |