| Phenotype: | Mauthner neuron NMDA glutamate receptor activity decreased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | Mauthner neuron |
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| Synonyms: | |
| Definition: | Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon. |
| Ontology: | Anatomy Ontology [ZFA:0009149] |
| Name: | NMDA glutamate receptor activity |
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| Synonyms: | N-methyl-D-aspartate selective glutamate receptor activity, NMDA receptor |
| Definition: | An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages. |
| Ontology: | GO: Molecular Function [GO:0004972] QuickGO AmiGO |
| Name: | decreased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is decreased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002302] |