Search Ontology:
GO: Cellular Component

platelet-derived growth factor receptor-ligand complex

Term ID
GO:1990270
Synonyms
  • PDGF receptor-ligand complex
  • PDGF-AA-receptor alpha complex
  • PDGF-AB-receptor alpha complex
  • PDGF-AB-receptor beta complex
  • PDGF-BB-receptor alpha complex
  • PDGF-BB-receptor alpha-beta complex
  • PDGF-BB-receptor beta complex
  • PDGF-CC-receptor alpha complex
  • PDGF-CC-receptor alpha-beta complex
  • PDGF-CC-receptor beta complex
  • PDGF-DD-receptor alpha-beta complex
  • PDGF-DD-receptor beta complex
  • receptor-ligand complex
Definition
A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes. 11331882
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
has_part
Phenotype
Phenotype caused by Genes