Search Ontology:
GO: Cellular Component

platelet-derived growth factor complex

Term ID
GO:1990265
Synonyms
  • PDGF complex
  • PDGF-AA dimer
  • PDGF-AB dimer
  • PDGF-BB dimer
  • PDGF-CC dimer
  • PDGF-DD dimer
Definition
A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD). 11331882
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
inverse has_part
Phenotype
Phenotype caused by Genes