ATP-binding cassette (ABC) transporter complex

Term ID

GO:0043190

Synonyms

• ABC-type efflux permease complex
• ABC-type efflux porter complex
• ABC-type uptake permease complex
• mating pheromone exporter

Definition

A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO