negative regulation of signal transduction by receptor internalization

Term ID

GO:0038011

Synonyms

negative regulation of signaling pathway by receptor endocytosis

Definition

Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands. (2)

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: negative regulation of signal transduction receptor internalization regulation of signal transduction by receptor internalization

negative regulation of signal transduction receptor internalization regulation of signal transduction by receptor internalization Show first 5 Terms
has subtype: negative regulation of insulin receptor signaling pathway by insulin receptor internalization

negative regulation of insulin receptor signaling pathway by insulin receptor internalization Show first 5 Terms
negatively regulates: signal transduction

signal transduction Show first 5 Terms

Phenotype

Phenotype caused by Genes