epidermal growth factor receptor signaling pathway

Term ID

GO:0007173

Synonyms

EGF receptor signaling pathway
EGF receptor signalling pathway
EGFR signaling pathway
epidermal growth factor receptor signalling pathway
ERBB1 signaling pathway
receptor tyrosine-protein kinase erbB-1 signaling pathway

Definition

The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: epidermal growth factor receptor activity

epidermal growth factor receptor activity Show first 5 Terms
is a type of: ERBB signaling pathway

ERBB signaling pathway Show first 5 Terms
has subtype: epidermal growth factor receptor signaling pathway involved in heart process epidermal growth factor receptor signaling pathway involved in lung development epidermal growth factor signaling pathway involved in forebrain neuron fate commitment ERBB2-EGFR signaling pathway ERBB4-EGFR signaling pathway

epidermal growth factor receptor signaling pathway involved in heart process epidermal growth factor receptor signaling pathway involved in lung development epidermal growth factor signaling pathway involved in forebrain neuron fate commitment ERBB2-EGFR signaling pathway ERBB4-EGFR signaling pathway Show first 5 Terms
negatively regulated by: negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor receptor signaling pathway Show first 5 Terms
positively regulated by: positive regulation of epidermal growth factor receptor signaling pathway

positive regulation of epidermal growth factor receptor signaling pathway Show first 5 Terms
regulated by: regulation of epidermal growth factor receptor signaling pathway

regulation of epidermal growth factor receptor signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes