antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent

Term ID

GO:0002490

Synonyms

• endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent
• TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
• TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway

Definition

The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. 15928678

References

Ontology

GO: Biological Process    QuickGO    AmiGO