amfenac

Term ID

CHEBI:75915

Synonyms

(2-amino-3-benzoylphenyl)acetic acid
(2-Amino-3-benzoylphenyl)essigsaeure
2-amino-3-benzoylbenzeneacetic acid
amfenac
amfenaco
amfenacum

Definition

An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.

References

CAS:51579-82-9
Drug_Central:154
KEGG:D07443
PMID:10850857
PMID:19897019
PMID:3540874
PMID:8320556
Patent:DE2324768
Patent:US4045576
Reaxys:2381781
Wikipedia:Amfenac

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: amino acid benzophenones oxo monocarboxylic acid primary amino compound substituted aniline

amino acid benzophenones oxo monocarboxylic acid primary amino compound substituted aniline Show first 5 Terms
has_role: antipyretic cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug

antipyretic cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug Show first 5 Terms
inverse has_functional_parent: bromfenac

bromfenac Show first 5 Terms
inverse is_conjugate_base_of: amfenac(1-)

amfenac(1-) Show first 5 Terms
is_conjugate_acid_of: amfenac(1-)

amfenac(1-) Show first 5 Terms

Phenotype

Phenotype resulting from amfenac

Phenotype where environments contain amfenac

Phenotype modified by environments containing amfenac

Human Disease Model