bromfenac

Term ID

CHEBI:240107

Synonyms

2-amino-3-(4-bromobenzoyl)benzeneacetic acid
[2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
bromfenac
bromfenaco
bromfenacum

Definition

Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure.

References

Beilstein:8335547
CAS:91714-94-2
DrugBank:DB00963
Drug_Central:401
KEGG:D07541
LINCS:LSM-5585
Patent:EP221753
Patent:US4683242
Wikipedia:Bromfenac

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: aromatic amino acid benzophenones organobromine compound substituted aniline

aromatic amino acid benzophenones organobromine compound substituted aniline Show first 5 Terms
has_functional_parent: amfenac

amfenac Show first 5 Terms
has_role: non-narcotic analgesic non-steroidal anti-inflammatory drug

non-narcotic analgesic non-steroidal anti-inflammatory drug Show first 5 Terms
inverse is_conjugate_base_of: bromfenac(1-)

bromfenac(1-) Show first 5 Terms
is_conjugate_acid_of: bromfenac(1-)

bromfenac(1-) Show first 5 Terms

Phenotype

Phenotype resulting from bromfenac

Phenotype where environments contain bromfenac

Phenotype modified by environments containing bromfenac

Human Disease Model