Search Ontology:
ChEBI
cortistatin A
- Term ID
- CHEBI:67171
- Synonyms
-
- (+)-cortistatin A
- (1R,2R,3S,5R)-3-(dimethylamino)-17beta-(isoquinolin-7-yl)-5,8alpha-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-diene-1,2-diol
- (1R,2R,3S,5R,8alpha,17beta)-3-(dimethylamino)-17-(isoquinolin-7-yl)-5,8-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-diene-1,2-diol
- Definition
- A member of the class of cortistatins that is substituted by hydroxy groups at positions 1 and 2, a dimethylamino group at the 3alpha position and an isoquinolin-7-yl group at the 17 position, with double bonds at the 9-11 and 10-19 positions (the 1R,2R,17beta enantiomer).
- References
-
- PMID:18479104
- PMID:20925326
- PMID:21539314
- PMID:21651309
- PMID:22879684
- Reaxys:10502377
- Ontology
- ChEBI ( EBI )
- is a type of
-
- inverse has_functional_parent
-
Phenotype
Phenotype resulting from cortistatin A
Phenotype where environments contain cortistatin A
Phenotype modified by environments containing cortistatin A
Human Disease Model