amrubicinol

Term ID

CHEBI:156204

Synonyms

(7S,9S)-9-amino-7-{[(2S,4S,5R)-4,5-dihydroxytetrahydro-2H-pyran-2-yl]oxy}-6,11-dihydroxy-9-(1-hydroxyethyl)-7,8,9,10-tetrahydrotetracene-5,12-dione

Definition

A diastereoisomeric mixture resulting from the formal reduction of the acetyl group at position 9 of amrubicin to the corresponding 1-hydroxyethyl group. The active metabolite of amrubicin in lung cancer patients.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: diastereoisomeric mixture quinone secondary alcohol tetracenes

diastereoisomeric mixture quinone secondary alcohol tetracenes Show first 5 Terms
has_functional_parent: amrubicin

amrubicin Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer topoisomerase II inhibitor

antineoplastic agent apoptosis inducer topoisomerase II inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from amrubicinol

Phenotype where environments contain amrubicinol

Phenotype modified by environments containing amrubicinol

Human Disease / Model Data