Search Ontology:
ChEBI

amrubicin

Term ID
CHEBI:135779
Synonyms
  • (1S,3S)-3-acetyl-3-amino-5,12-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2-deoxy-beta-D-erythro-pentopyranoside
  • (7S,9S)-9-acetyl-9-amino-7-{[(2S,4S,5R)-4,5-dihydroxytetrahydro-2H-pyran-2-yl]oxy}-6,11-dihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione
  • amrubicin
  • amrubicina
  • amrubicine
  • amrubicinum
  • SM-5887
Definition
A synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from amrubicin
Phenotype where environments contain amrubicin
Phenotype modified by environments containing amrubicin
Human Disease / Model Data