| Term: | renal tubule pyroptotic inflammatory response |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | renal tubule |
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| Synonyms: | mesonephric tubule, renal tubules |
| Definition: | Renal duct that collects filtrate from the renal corpuscle and transports it to the collecting duct. Different parts of the renal tubule reabsorb specific components of the filtrate to leave only waste. |
| Ontology: | Anatomy Ontology [ZFA:0001287] |
| Name: | pyroptotic inflammatory response |
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| Synonyms: | pyroptosis |
| Definition: | A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. |
| Ontology: | GO: Biological Process [GO:0070269] QuickGO AmiGO |