Search Ontology:
GO: Biological Process

pyroptotic inflammatory response

Term ID
GO:0070269
Synonyms
  • pyroptosis
Definition
A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. (3)
References
  • Reactome:R-HSA-5620971
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
Phenotype
Phenotype caused by Genes
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